| Sensitive Electrochemiluminescence sensor based on Luminol/QDs nanocomposite embeded in hydrogel for MC-LR detection in water samples |
| کد مقاله : 1556-IWWA |
| نویسندگان |
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فائزه پاکپور *1، رحمان حلاج2 1دانشجوی دانشگاه کردستان 2دانشگاه کردستان |
| چکیده مقاله |
| The increasing occurrence of cyanobacterial toxins in aquatic environments has raised concerns regarding the contamination of drinking and irrigation water by microcystin-LR (MC-LR). MC-LR represents a potential threat to human health and environmental safety, highlighting the need for sensitive methods capable of detecting trace levels of this contaminant. Electrochemiluminescence (ECL) has emerged as a promising sensing strategy owing to its high sensitivity and favorable signal-to-background characteristics. Among various ECL emitters, quantum dots (QDs) have attracted considerable attention because of their tunable optical and biocompatibility, and convenient surface functionalization. Luminol is another well-established ECL-active compound that can serve as an effective signal-generating component in analytical sensing systems. In this work, a ECL sensor was developed for the sensitive detection of MC-LR by integrating a quantum dot/luminol nanocomposite with a biocompatible hydrogel-based sensing interface. The sensing interface was engineered to provide selective recognition of MC-LR and efficient transduction of the target-binding event into an ECL signal. Upon interaction with the target analyte, the sensing platform exhibited an enhanced ECL response, enabling sensitive determination of MC-LR. The developed sensor demonstrated favorable analytical performance, including good sensitivity and stability toward MC-LR. A concentration-dependent ECL response was observed over the investigated range from fM to nM with a good low detection limit (S/N ratio of 3) for MC-LR detection. Moreover, the applicability of the proposed platform was examined using water samples, yielding satisfactory results. |
| کلیدواژه ها |
| Microcystin-LR, Electrochemiluminescence, Luminol, Quantum dots, hydrogel. |
| وضعیت: پذیرفته شده برای ارسال فایل های ارائه پوستر |
